Exosome Lipidomics & Metabolomics

Exosome Lipidomics & Metabolomics

詳細介紹

TBAL has long been dedicated to disease-related research. We offer comprehensive analytical services for exosome lipidomics and metabolomics, making it easier for you to identify potential biomarkers.

The Importance of Exosome Lipidomics & Metabolomics Analysis

Exosomes are composed of various elements, including proteins, nucleic acids, lipids, and other metabolites, facilitating cell-to-cell communication. In vivo, lipids typically act as mediums for signal transduction. More importantly, exosomes contain several unique lipids not found in recipient cells, which can be used as novel biomarkers for disease diagnosis and prognosis. Besides lipids, exosomes also carry a wide range of other metabolites that play an active role in cancer progression and can be used for biomarker discovery. Thus, monitoring exosome lipidomics and metabolomics is crucial for studying the onset and progression of metabolic diseases. Since the lipid and metabolite contents of exosomes differ from those of the parent cells and change during physiological processes, characterizing the lipidomics of different biofluids is the most feasible way to identify sensitive and specific biomarkers.

Exosome Lipidomics & Metabolomics Service

TBAL supports accurate and sensitive detection of metabolites from exosomes, facilitating biomarker screening. We have specialized experts and well-established platforms that allow us to extract the most information from your exosomes quickly and efficiently. The advantages of our exosome lipidomics and metabolomics service are as follows:

  • Effective Sample Isolation: We provide the optimal method for exosome isolation from various input samples, including cells, culture supernatant, plasma (whole blood, serum), etc.
  • Diverse Identification of Exosomes: We offer tailored solutions for morphology, particle size, exosome markers, labeling, and tracking analysis.
  • High Throughput Analysis: We provide professional exosome lipidomics and metabolomics analysis services with reliable and sensitive results using cutting-edge technologies. These technologies include thin layer chromatography (TLC), high performance liquid chromatography (HPLC), NMR spectroscopy, mass spectrometry, reverse phase chromatography, etc.
  • Rapid Delivery Time with Detailed Project Report: We ensure timely delivery with comprehensive project reports.
  • Professional Communication and Competitive Prices: We offer excellent communication and competitive pricing for our services.

Figure 1 Characterization of the metabolite content of human plasma Exosome-Like Vesicles (P ELVs) (Panel A) or PANC 1 cell culture media (CCM ELVs) (Panel B). (Altadill et al., 2016)

TBAL is dedicated to cost-effective, high throughput biomarker development for diseases. We aim to add value to clinical and translational studies through our work. We will continue to innovate and develop new methods to meet your needs in biomarker discovery. Please contact us for more details and to learn how our services can support your research.

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References:
Kumari S.; Singh A. Urinary exosomal lipidomics reveals markers for diabetic nephropathy. Current metabolomics. 2018, 6(2): 131-139.
Tatiana Altadill T.; Campoy I. Enabling metabolomics based biomarker discovery studies using molecular phenotyping of exosome-like vesicles. PLOS One. 2016, 11(3): e0151339.